Hairy cell leukemia is commonly treated with which regimen?

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Multiple Choice

Hairy cell leukemia is commonly treated with which regimen?

Explanation:
Hairy cell leukemia responds exceptionally well to purine analog chemotherapy. The standard frontline regimen is cladribine, also known as 2CDA (2-chlorodeoxyadenosine), given as a short IV course. It achieves complete remissions in most patients and often provides durable remissions. Other drugs like methotrexate or cyclophosphamide aren’t the typical first-line choices for this disease, and rituximab is more commonly used in relapsed or refractory cases. So the commonly used regimen is cladribine (2CDA).

Hairy cell leukemia responds exceptionally well to purine analog chemotherapy. The standard frontline regimen is cladribine, also known as 2CDA (2-chlorodeoxyadenosine), given as a short IV course. It achieves complete remissions in most patients and often provides durable remissions. Other drugs like methotrexate or cyclophosphamide aren’t the typical first-line choices for this disease, and rituximab is more commonly used in relapsed or refractory cases. So the commonly used regimen is cladribine (2CDA).

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