Hypercalcemia can present with which of the following renal-related disorders as a manifestation?

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Multiple Choice

Hypercalcemia can present with which of the following renal-related disorders as a manifestation?

Explanation:
High calcium levels impair the kidney’s ability to concentrate urine by causing resistance to antidiuretic hormone in the collecting ducts, which reduces water reabsorption through Aquaporin-2 channels. This leads to polyuria with dilute urine and compensatory thirst—classic for nephrogenic diabetes insipidus. Among the options, this renal-related disorder best fits hypercalcemia as a manifestation. Hyperkalemia, hyponatremia, and hypocalcemia are not typical direct consequences of elevated calcium; they reflect other processes or electrolyte disturbances.

High calcium levels impair the kidney’s ability to concentrate urine by causing resistance to antidiuretic hormone in the collecting ducts, which reduces water reabsorption through Aquaporin-2 channels. This leads to polyuria with dilute urine and compensatory thirst—classic for nephrogenic diabetes insipidus. Among the options, this renal-related disorder best fits hypercalcemia as a manifestation. Hyperkalemia, hyponatremia, and hypocalcemia are not typical direct consequences of elevated calcium; they reflect other processes or electrolyte disturbances.

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