In polymyalgia rheumatica, which of the following CK levels is typical?

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Multiple Choice

In polymyalgia rheumatica, which of the following CK levels is typical?

Explanation:
Creatine kinase goes up when muscle fibers are injured. In polymyalgia rheumatica, the pain and stiffness come from inflammation of periarticular tissues and synovitis around the shoulders and hips, not from primary muscle fiber damage. So there isn’t significant muscle breakdown to release CK, and levels are typically normal. If CK were elevated, consider a coexisting inflammatory myopathy or another cause of muscle injury rather than PMR alone (for example, polymyositis, statin myopathy, or strenuous exercise).

Creatine kinase goes up when muscle fibers are injured. In polymyalgia rheumatica, the pain and stiffness come from inflammation of periarticular tissues and synovitis around the shoulders and hips, not from primary muscle fiber damage. So there isn’t significant muscle breakdown to release CK, and levels are typically normal. If CK were elevated, consider a coexisting inflammatory myopathy or another cause of muscle injury rather than PMR alone (for example, polymyositis, statin myopathy, or strenuous exercise).

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