What is the recommended RBC preparation to prevent febrile transfusion reactions?

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Study for the Step 3 UWSA Exam with our challenging quiz. Prepare with detailed explanations for each question, ensuring you're well-equipped for success. Enhance your understanding and boost your exam confidence!

Multiple Choice

What is the recommended RBC preparation to prevent febrile transfusion reactions?

Febrile transfusion reactions are mainly caused by donor white blood cells and the cytokines they release. The best way to prevent these reactions is to remove leukocytes from the blood product before transfusion, giving leukocyte-reduced (prestorage leukoreduced) red blood cells. Irradiation inactivates donor T cells to prevent transfusion-associated GVHD, which is a separate risk and not the primary strategy to prevent febrile reactions. Washed red blood cells remove donor plasma proteins and can help with some reactions, but leukoreduction is the most effective measure specifically for preventing febrile nonhemolytic transfusion reactions.

What is the recommended RBC preparation to prevent febrile transfusion reactions?

Study for the Step 3 UWSA Exam with our challenging quiz. Prepare with detailed explanations for each question, ensuring you're well-equipped for success. Enhance your understanding and boost your exam confidence!

What is the recommended RBC preparation to prevent febrile transfusion reactions?

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